Intrinsic fluorescence of selenium nanoparticles for cellular imaging applications

A Khalid; P Tran; R Norello; D Simpson; A O'Connor; S Tomljenovic-Hanic

Journal article

Intrinsic fluorescence of selenium nanoparticles for cellular imaging applications

A Khalid, P Tran, R Norello, D Simpson, A O'Connor, S Tomljenovic-Hanic

Nanoscale | Royal Society of Chemistry | Published : 2016

DOI: 10.1039/c5nr08771f

Abstract

Nanoparticles hold great potential in contributing to high-resolution bioimaging as well as for biomedical applications. Although, selenium (Se) nanoparticles (NPs) have been investigated owing to their potential roles in therapeutics, the imaging capability of these NPs has never been explored. This manuscript identifies the intrinsic fluorescence of Se NPs, which is highly beneficial for nanoscale imaging of biological structures. The emission of individual NPs and its evolution with time is explored. The photoluminescence spectra has revealed visible to near infrared emission for Se NPs. The work finally reflects on the role of this intrinsic fluorescence for in vitro imaging and tracking..

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University of Melbourne Researchers

Asma Khalid Author

David Simpson Author

Andrea O'Connor Author

Snjezana Tomljenovic-Hanic Author

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Grants

Awarded by Australian Research Council

Funding Acknowledgements

The authors acknowledge Jean-Philippe Tetienne for measuring the lifetime of the Se NPs. This work was partly supported with the assistance of the Australian Research Council (ARC) under Discovery Project Scheme no. DP1096288, University of Melbourne Interdisciplinary Seed Grant, by an award under the Merit Allocation Scheme on the National Facility of the National Computational Infrastructure and CASS Foundation grant. A. K. is partly supported by Melbourne Research Scholarships awarded by The University of Melbourne. P.A.T. is supported by University of Melbourne McKenzie Fellowship. S.T-H. is supported by an ARC Australian Research Fellowship (DP1096288).